In the face of a burgeoning global population, the agricultural sector is under immense pressure to boost productivity while maintaining environmental sustainability. A recent review published in the Nepal Journal of Biotechnology sheds light on the potential of biofertilizers to revolutionize farming practices, offering a promising alternative to chemical fertilizers.
Biofertilizers, formulated from beneficial microorganisms such as nitrogen-fixing bacteria, phosphate solubilizers, and plant growth-promoting bacteria, play a pivotal role in enhancing nutrient levels, promoting root growth through phytohormone production, and increasing plant resistance to abiotic stress. These microorganisms contribute significantly to crop yield and soil fertility.
The review, led by Muhammad Junaid from the Institute of Biological Sciences at Khwaja Fareed University of Engineering and Information Technology in Pakistan, highlights the mechanisms behind biofertilizers and their impact on crop yield and soil health. “Greenhouse and field research indicate that single-strain and multi-strain microbial inoculants, including Effective Microorganisms (EM), can increase microbial diversity in soil, boost organic matter content, and enhance water retention,” Junaid explains.
However, the responses in yield can vary significantly depending on factors such as crop species, soil properties, climate, and management practices. This variability, along with challenges like inadequate shelf life and regulatory barriers, has limited the widespread application of biofertilizers.
The review also explores innovative solutions to address these challenges, including microbial encapsulation, Artificial Intelligence-based data-driven optimization, and the use of genome editing tools like CRISPR to improve the stability, efficacy, and scalability of biofertilizer solutions.
The commercial implications for the agriculture sector are substantial. As the demand for sustainable and eco-friendly farming practices grows, biofertilizers present a lucrative opportunity for agribusinesses to diversify their product offerings and cater to environmentally conscious consumers. Furthermore, the integration of advanced technologies like AI and CRISPR can drive innovation and create new markets within the biofertilizer industry.
This research not only underscores the potential of biofertilizers to transform agriculture but also highlights the need for further investigation and technological advancements to overcome existing challenges. As the global population continues to rise, the adoption of sustainable farming practices will be crucial in ensuring food security and environmental preservation.
The insights provided by this review could shape future developments in the field, paving the way for a more sustainable and productive agricultural sector. With continued research and innovation, biofertilizers have the potential to become a cornerstone of modern farming practices, benefiting both the environment and the economy.

